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Automated brain tissue segmentation of magnetic resonance images in multiple sclerosis

Doctoral thesis “Automated brain tissue segmentation of magnetic resonance images in multiple sclerosis”   By Sergi Valverde Supervised by Dr. Arnau Oliver, Dr. Xavier Lladó   Abstract Multiple Sclerosis (MS) is the most common chronic immune-mediated disabling neurological disease affecting the central nervous system, in which the insulating covers of the nerve cells in the spinal chord and brain are damaged. MS is characterized by the presence of lesions in the brain, predominantly in the white matter (WM) tissue of the brain. Due to the sensitivity of structural Magnetic Resonance Imaging (MRI) disseminating WM lesions in time and space, it…