{"id":2877,"date":"2014-07-08T08:00:29","date_gmt":"2014-07-08T07:00:29","guid":{"rendered":"http:\/\/vicorob.udg.edu\/?p=2877"},"modified":"2014-07-08T08:00:29","modified_gmt":"2014-07-08T07:00:29","slug":"konstantin-korotkov-defends-his-phd-thesis-automatic-change-detection-in-multiple-pigmented-skin-lesions","status":"publish","type":"post","link":"https:\/\/vicorob.udg.edu\/ca\/konstantin-korotkov-defends-his-phd-thesis-automatic-change-detection-in-multiple-pigmented-skin-lesions\/","title":{"rendered":"Konstantin Korotkov defends his PhD thesis &#8220;Automatic change detection in multiple pigmented skin lesions&#8221;"},"content":{"rendered":"<p>Malignant melanoma is the rarest and deadliest of skin cancers causing three times more deaths than all other skin-related malignancies combined. Fortunately, in its early stages, it is completely curable, making a total body skin examination (TBSE) a fundamental procedure for many patients. During TBSE, dermatologists look for pigmented skin lesions (PSLs) exhibiting typical melanoma signs as well as PSLs undergoing the rapid changes characteristic of cancer. Accompanied by clinical and dermoscopic baseline photography, a TBSE can be very tedious and time-consuming, especially for patients with numerous lesions. In addition, establishing correct body-to-image and image-to-image lesion correspondences can be extremely difficult.<\/p>\n<p>&nbsp;<\/p>\n<p>Despite the advances in body scanning techniques, automated assistance tools for TBSEs have not received due attention. This fact is emphasized in our literature review covering the area of computerized analysis of PSL images. In this review, we summarize various approaches for implementing PSL computer-aided diagnosis systems and discuss their standard workflow components.<\/p>\n<p>&nbsp;<\/p>\n<p>Aiming at the automation of TBSEs, we have designed and built a total body scanner to acquire skin surface images using cross-polarized light. Equipped with 21 low-cost high-resolution cameras and a turntable, this scanner automatically acquires a set of overlapping images, covering 85-90% of the patient&#8217;s skin surface. A one-shot extrinsic calibration of all the cameras is carried out using a specifically designed color-coded calibration pattern. Furthermore, we have developed an algorithm for the automated mapping of PSLs and their change estimation between explorations. The maps produced relate images of individual lesions with their locations on the patient&#8217;s body, solving the body-to-image and image-to-image correspondence problem in TBSEs.<\/p>\n<p>&nbsp;<\/p>\n<p>The initial tests of the scanner showed that it can be successfully applied for automated mapping and temporal monitoring of multiple lesions: PSLs relevant for follow-up were repeatedly mapped in several explorations. Moreover, during the baseline image comparison, all lesions with artificially induced changes were correctly identified as \u201cevolved\u201d. In order to perform a wider clinical trial with a diverse skin image set, the scanner has been installed in the Melanoma Unit at the Clinic Hospital of Barcelona.<\/p>\n<p>_________________________<\/p>\n<p>&nbsp;<\/p>\n<p>El melanoma maligne \u00e9s el m\u00e9s rar i mortal de tots els c\u00e0ncers de pell, causant tres vegades m\u00e9s morts que el conjunt de totes les altres malalties malignes de la pell. Afortunadament, en les primeres etapes, \u00e9s completament curable, fent de les exploracions de pell a nivell de cos complert (TBSE, de l\u2019angl\u00e8s Total Body Skin Examination) un proc\u00e9s fonamental per a molts pacients. Durant el TBSE, els dermat\u00f2legs busquen els signes t\u00edpics de melanoma en les lesions pigmentades de la pell (PSL, Pigmented Skin Lesions), aix\u00ed com PSLs sotmesos als r\u00e0pids canvis caracter\u00edstics del c\u00e0ncer. Conjuntament amb la fotografia de refer\u00e8ncia cl\u00ednica i dermatosc\u00f2pica, el c\u00e0lcul de TBSE pot ser molt tedi\u00f3s i lent, especialment per a pacients amb un gran nombre de lesions. A m\u00e9s a m\u00e9s, establir correspond\u00e8ncies correctes entre el cos i les imatges, i entre les diferents imatges, per a cadascuna de les lesions, pot \u00e9sser d\u2019extrema dificultat.<\/p>\n<p>&nbsp;<\/p>\n<p>Malgrat els aven\u00e7os en les t\u00e8cniques d\u2019escaneig cutani, les eines per a realitzar TBSEs de forma autom\u00e0tica no han rebut massa atenci\u00f3. Aquest fet es posa de relleu en la nostra revisi\u00f3 de la literatura, que cobreix l&#8217;\u00e0rea de l\u2019an\u00e0lisi per computador d&#8217;imatges de PSL. En aquesta revisi\u00f3, es resumeixen v\u00e0ries aproximacions per a la implementaci\u00f3 del diagn\u00f2stic assistit per ordinador, comentant-ne els seus components principals.<\/p>\n<p>&nbsp;<\/p>\n<p>Amb l&#8217;objectiu de l&#8217;automatitzaci\u00f3 de TBSEs, hem dissenyat i constru\u00eft un esc\u00e0ner corporal de cobertura total per adquirir imatges de la superf\u00edcie de la pell utilitzant llum amb polaritzaci\u00f3 creuada. Equipat amb 21 c\u00e0meres d&#8217;alta resoluci\u00f3 de baix cost i una plataforma girat\u00f2ria, aquest esc\u00e0ner adquireix autom\u00e0ticament un conjunt d&#8217;imatges amb solapament, que cobreix el 85&#8211;90% de la superf\u00edcie de la pell del pacient. La calibraci\u00f3 extr\u00ednseca del sistema es du a terme utilitzant una sola imatge de cada c\u00e0mera i un patr\u00f3 de calibratge amb un codi de colors dissenyat espec\u00edficament.per a lalitzat satisfactoriament mapeig senyat especs principals. s per a cadascuna de les lesions pot d&#8217;ell de cos complert () A m\u00e9s, hem desenvolupat un algoritme pel mapeig autom\u00e0tic de les PSLs i l\u2019estimaci\u00f3 dels canvis entre exploracions. Els mapes produ\u00efts relacionen les imatges de les lesions individuals amb la seva ubicaci\u00f3 en el cos del pacient, resolent el problema de correspond\u00e8ncia del cos a la imatge i d&#8217;imatge a imatge en TBSEs. Actualment, l&#8217;esc\u00e0ner es limita a pacients amb esc\u00e0s p\u00e8l corporal.<\/p>\n<p>&nbsp;<\/p>\n<p>Els tests inicials de l\u2019esc\u00e0ner mostren que aquest pot \u00e9sser utilitzat satisfact\u00f2riament pel mapeig autom\u00e0tic i el control de canvis temporal de m\u00faltiples lesions: els PSLs importants per a realitzar-ne el seguiment han estat mapejats successivament en les diverses exploracions. D\u2019altra banda, durant la comparaci\u00f3 d\u2019imatges, totes les lesions amb canvis artificials introdu\u00efts han estat correctament identificades com \u201cevolucionades\u201d. Per tal de desenvolupar estudis cl\u00ednics m\u00e9s amplis, amb diferents tipus de pell, l\u2019esc\u00e0ner s\u2019ha instal\u00b7lat a la Unitat de Melanoma de l\u2019Hospital Cl\u00ednic de Barcelona.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Malignant melanoma is the rarest and deadliest of skin cancers causing three times more deaths than all other skin-related malignancies combined. Fortunately, in its early stages, it is completely curable, making a total body skin examination (TBSE) a fundamental procedure for many patients. During TBSE, dermatologists look for pigmented skin lesions (PSLs) exhibiting typical melanoma&hellip;&nbsp;<a href=\"https:\/\/vicorob.udg.edu\/ca\/konstantin-korotkov-defends-his-phd-thesis-automatic-change-detection-in-multiple-pigmented-skin-lesions\/\" rel=\"bookmark\"><span class=\"screen-reader-text\">Konstantin Korotkov defends his PhD thesis &#8220;Automatic change detection in multiple pigmented skin lesions&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":2906,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[75,12,58],"tags":[76,77,78],"class_list":["post-2877","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-imaging-lab","category-news","category-scientific-results","tag-medical-imaging","tag-melanoma-detection","tag-skin-cancer"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Konstantin Korotkov defends his PhD thesis &quot;Automatic change detection in multiple pigmented skin lesions&quot; - Vicorob<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vicorob.udg.edu\/konstantin-korotkov-defends-his-phd-thesis-automatic-change-detection-in-multiple-pigmented-skin-lesions\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Konstantin Korotkov defends his PhD thesis &quot;Automatic change detection in multiple pigmented skin lesions&quot; - Vicorob\" \/>\n<meta property=\"og:description\" content=\"Malignant melanoma is the rarest and deadliest of skin cancers causing three times more deaths than all other skin-related malignancies combined. 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